Chihiro Kondo Selected Research

ME 3277

4/2005

Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2).

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Chihiro Kondo Research Topics

Disease

9	Neoplasms (Cancer) 06/2015 - 06/2006
9	Stomach Neoplasms (Stomach Cancer) 06/2015 - 02/2011
6	Neoplasm Metastasis (Metastasis) 01/2013 - 06/2006
5	Colorectal Neoplasms (Colorectal Cancer) 02/2014 - 01/2011
4	Breast Neoplasms (Breast Cancer) 01/2015 - 10/2004
2	Fibrosarcoma 01/2015 - 06/2006
2	Esophageal Neoplasms (Esophageal Cancer) 10/2011 - 01/2011
2	Neutropenia 08/2011 - 02/2011
2	Jaundice (Icterus) 08/2011 - 07/2011
2	Disease Progression 05/2011 - 01/2003
2	Endometrial Neoplasms (Endometrial Cancer) 03/2006 - 11/2004
1	Ascites 01/2013
1	Disseminated Intravascular Coagulation 12/2011
1	Rectal Neoplasms (Rectal Cancer) 12/2011
1	Leukopenia 08/2011
1	Thrombocytopenia (Thrombopenia) 08/2011
1	Hematologic Neoplasms (Hematological Malignancy) 08/2011
1	Fatigue 07/2011
1	Anorexia 07/2011
1	Colonic Neoplasms (Colon Cancer) 07/2011
1	Diarrhea 05/2011
1	Lung Neoplasms (Lung Cancer) 06/2006
1	Adenocarcinoma 03/2006
1	Schizophrenia (Dementia Praecox) 01/2003

Drug/Important Bio-Agent (IBA)

5	Cisplatin (Platino)FDA LinkGeneric 06/2013 - 03/2006
5	Paclitaxel (Taxol)FDA LinkGeneric 05/2011 - 11/2004
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 02/2014 - 01/2011
4	Irinotecan (Camptosar)FDA LinkGeneric 12/2011 - 05/2011
3	Trastuzumab (Herceptin)FDA Link 06/2015 - 05/2011
3	Cetuximab (Erbitux)FDA Link 12/2011 - 07/2011
3	Fluorouracil (Carac)FDA LinkGeneric 12/2011 - 07/2011
3	Docetaxel (Taxotere)FDA Link 10/2011 - 01/2011
3	PlatinumIBA 06/2011 - 11/2004
3	Proteins (Proteins, Gene)FDA Link 09/2005 - 10/2004
2	Cathepsin LIBA 01/2015 - 06/2006
2	S-1 plus cisplatinIBA 08/2014 - 06/2013
2	Bevacizumab (Avastin)FDA Link 02/2014 - 12/2011
2	Capecitabine (Xeloda)FDA Link 06/2013 - 01/2013
2	human ERBB2 proteinIBA 04/2013 - 05/2011
2	Leucovorin (Folinic Acid)FDA Link 12/2011 - 07/2011
2	BilirubinIBA 08/2011 - 07/2011
2	Carboplatin (JM8)FDA LinkGeneric 03/2006 - 11/2004
2	leucyl-cystinyl aminopeptidaseIBA 03/2006 - 11/2004
2	Complementary DNA (cDNA)IBA 03/2006 - 11/2004
1	CathepsinsIBA 01/2015
1	CarbohydratesIBA 02/2014
1	AntigensIBA 02/2014
1	Dacarbazine (DIC)FDA LinkGeneric 12/2011
1	Taxoids (Taxanes)IBA 06/2011
1	Lapatinib (GW572016)FDA Link 05/2011
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2011
1	A-factor (Streptomyces)IBA 03/2006
1	Peptides (Polypeptides)IBA 09/2005
1	AnionsIBA 09/2005
1	Multidrug Resistance-Associated Protein 2IBA 09/2005
1	ProdrugsIBA 04/2005
1	ME 3229IBA 04/2005
1	ME 3277IBA 04/2005
1	perospironeIBA 01/2003
1	Antipsychotic Agents (Antipsychotics)IBA 01/2003
1	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2003

Therapy/Procedure

11	Drug Therapy (Chemotherapy) 02/2014 - 11/2004
6	Combination Drug Therapy (Combination Chemotherapy) 08/2014 - 05/2011
3	Therapeutics 10/2011 - 01/2003
1	Induction Chemotherapy 10/2011
1	Drug Tapering 05/2011